Greece4.0 is a Network of Excellence for the Development, Dissemination and Application of Digital Transformation Technologies in the Greek Manufacturing Industry. The goal of Greece4.0 is to help Greek manufacturing industry in their digital transformation towards the design and implementation of smart practices in their production facilities, related to digital automation. The Greece4.0 project will serve as Industry 4.0 test pillar providing the required infrastructure and knowledge to develop, test and validate services such as: smart sensors, Industrial IoT platforms, Digital Twins, control systems and robotics and Artificial Intelligence in a safe and cost-effective approach for companies. The Greece4.0 partners will utilise and improve know-how obtained through various European research initiatives and innovation on advanced production and digital technologies, combining the features of cyber-physical production with Artificial Intelligence for carrying out advanced production processes.